Cardiac Tissue Model
Beating Cardiac Bodies – a complete workflow
Stem cell derived cardiomyocytes gain more and more attention in the field of cardiovascular research, disease modeling and drug development.
The CERO 3D Incubator & Bioreactor platform allows the workflow with stem cell expansion in homogeneous aggregates followed by direct induction into a high number of beating cardiac bodies. The expansion of pluripotent stem cells and subsequent cardiac induction/differentiation in CERO 3D results in a much higher cell quality, homogeneity, integrity and yield compared to traditional orbital shakers.
CERO 3D versus Orbital shaker – differentiation of murine embryonic stem cell derived cardiomyocytes 3, 8 and 13 days after cardiac induction.
- Homogeneous 3D aggregates in suspension
- Expansion and differentiation in the same CEROtube
- Easy to handle & standardize
- Highest yield
- No substrate required
- More relevance for drug treatments
- More relevance for disease modeling
Purified and homogeneous cardiac bodies generated in CERO 3D Incubator & Bioreactor are a perfect tool for disease modeling and drug discovery. The pure cardiomyocytes can also be used in 2D downstream monolayer applications.